MxP^®Quant HR Xpress kit

MxP^®Quant HR Xpress kit

High resolution with high throughput

The MxP^® Quant HR Xpress kit is the first high throughput, standardized solution for broad lipid and metabolic profiling on Q Exactive™ mass spectrometers. It provides quantification of more than 360 metabolites and lipids from 11 compound classes covering central metabolic pathways.

MxP® Quant 500 kit validated on Sciex Triple Quad 7500 LC MS/MS System

High resolution with high throughput

The MxP® Quant HR Xpress kit is the first high throughput, standardized solution for broad lipid and metabolic profiling on Q Exactive™ mass spectrometers. It provides quantification of more than 360 metabolites and lipids from 11 compound classes covering central metabolic pathways.

Plug & play metabolomics

Methods for your instrument included
Ready to measure after a few hours
Automated signal identiﬁcation, quantiﬁcation & validation

Get functional insights

Data handling and statistics packages available
Support on biological interpretation available

Double your throughput

Runtime per sample < 12 minutes
Rapid sample preparation with minimal personal involvement

Quantitative & reproducible

Inter-laboratory, inter-instrument, and longitudinal reproducibility
Technology proven in international ring trial
> 1000 peer-reviewed publications utilizing kit technology

Standards and consumables

Patented 96-well filter plates with integrated internal standards
Calibration standards and quality controls
Test samples for system suitability test

Methods and protocols

Quick-start guide and user manual
Protocols for different matrices
Instrument-specific methods

WebIDQ™ – Workflow manager

Cloud-based software (on-premise option also available)
Complete experimental process guidance
Automated quantification, technical validation and report generation
MetaboINDICATOR™ with biologically relevant metabolite sums and ratios

LC column and MS systems

Compatible with Thermo Exactive, Exactive focus, Exactive Plus, Exactive HF
Validated LC column
Compatible with ultra high performance liquid chromatography (UHPLC)

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Covered metabolites an lipids

Small molecules: 21 amino acids, 21 biogenic amines, 1 monosaccharide
Polar lipids: 172 phosphatidylcholines, 24 lysophosphatidylcholines, 31 sphingomyelins, 9 ceramides
Neutral lipids: 11 acylcarnitines, 18 diglycerides, 42 triglycerides, 14 cholesteryl esters

The Quant HR Xpress kit covers metabolite and lipid classes of importance to the research fields of cardiology, hepatology, neurology, oncology, diabetes, nutrition and many more. See our Literature section for more detail.

Small molecules

Amino acid (20)
Biogenic amines (21)
Hexose (1)

Polar lipids

Phosphatidylcholines (172)
Lysophosphatidylcholines (24)
Sphingomyelins (31)
Ceramides (9)

Neutral lipids

Acylcarnitines (11)
Cholesteryl esters (14)
Diglycerides (18)
Triglycerides (42)

Download complete list

Application: Functional Microbiomics and Foodomics

Unraveling the Interaction of Lifestyle, Microbiota, Metabolism, and Health

Investigations of the gut-liver, gut-heart, and gut-brain axis have become of increased interest as researchers become to understand the role of the microbiota and its effect on many organ systems. As metabolic profiles can be obtained from biofluids, metabolomics can provide information about microbiota-related processes where metagenomics studies may not be possible. The MxP® Quant 500 includes microbiota-derived secondary bile acids, which have different signaling properties than primary bile acids which are synthetized by the liver.

MetaboINDICATOR™

Translate metabolomics into knowledge with one click

Calculating and understanding metabolite sums and ratios makes your biological data interpretation easier and more comprehensive. That is why we created MetaboINDICATOR™ as an add-on tool to WebIDQ. With one click you can find out how metabolite sums and ratios are associated with related biological functions so your data has meaningful impact.

MetaboINDICATOR™ is more than an additional dimension to your data analysis; it unravels the scientiﬁc context behind your data. All in one click.

More about MetaboINDICATOR